WebJan 31, 2024 · Some drugs reduce the stimulation of vestibular receptors, inhibit the function of the labyrinth (diphenhydramine, promethazine), and are used for motion sickness, in particular, vertigo. Because scopolamine potently prevents motion sickness, the anticholinergic properties of H 1-antagonists may be largely responsible for this effect. … Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, antipsychotic, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold and may also be used for sedating people … See more Promethazine has a variety of medical uses, including: • Sedation • For nausea and vomiting associated with anesthesia or chemotherapy. It is commonly used postoperatively as an See more Promethazine in overdose can produce signs and symptoms including CNS depression, hypotension, respiratory depression See more Solid promethazine hydrochloride is a white to faint-yellow, practically odorless, crystalline powder. Slow oxidation may occur upon prolonged exposure to air, usually causing blue … See more Promethazine was first synthesized by a group at Rhone-Poulenc (which later became part of Sanofi) led by Paul Charpentier in the early 1940s. The team was seeking to improve on diphenhydramine; the same line on medical chemistry … See more Some documented side effects include: • Tardive dyskinesia, pseudoparkinsonism, acute dystonia (effects due to dopamine D2 receptor antagonism) • Confusion in the elderly • Drowsiness, dizziness, fatigue, more rarely vertigo See more Promethazine, a phenothiazine derivative, is structurally different from the neuroleptic phenothiazines, with similar but different effects. It acts primarily as a strong antagonist of the H1 receptor (antihistamine, Ki = 1.4 nM ) and a moderate See more As of July 2024, it is marketed under many brand names worldwide: Allersoothe, Antiallersin, Anvomin, Atosil, Avomine, Closin N, Codopalm, Diphergan, Farganesse, Fenazil, … See more
Promethazine - Wikipedia
http://patientsafety.pa.gov/ADVISORIES/documents/200703_07.pdf WebPromethazine is designed to block receptors in your brain that can cause nausea and vomiting called histamine (H1) receptors. When chemotherapy is given, it can cause … tattoos turn off
Phenergan (Promethazine Injection) Information - Drugs.com
WebMar 7, 2024 · H1 receptors in central nervous system areas include the area postrema and vomiting center in the vestibular nucleus. Also, many of the antihistamines have anticholinergic properties that block muscarinic … WebApr 21, 2024 · Phenergan, either orally or by suppository, is useful for: Perennial and seasonal allergic rhinitis. Vasomotor rhinitis. Allergic conjunctivitis due to inhalant allergens and foods. Mild, uncomplicated allergic skin manifestations of urticaria and angioedema. Amelioration of allergic reactions to blood or plasma. Dermographism. WebJul 21, 2024 · Promethazine is a medication used to manage and treat allergic conditions, nausea and vomiting, motion sickness, and sedation. It also has off-label uses for nausea … the carpenters arms south marston swindon