WebThe aim of the present study was to investigate the correlation between the dosage and duration of treatment with phenytoin and the occurrence of cerebellar atrophy. Sixty-six patients were studied and had their tomographies analyzed for cerebellar atrophy. WebJan 20, 2024 · Multiple sclerosis, in which damage to the insulating membrane (myelin) that wraps around and protects nerve cells can involve the cerebellum. Acquired diseases that …
Cerebellar Atrophy and Dilantin - Consumer Justice Foundation
WebCerebellar degeneration is a disorder that affects nerves in the back of your brain. It can lead to balance issues or difficulty with speech and eyesight. Cerebellar degeneration can be the result of several health conditions like alcohol use disorder or cancer. Appointments 866.588.2264 Appointments & Locations Request an Appointment WebPhenytoin is an effective anticonvulsant for focal epilepsy. Its use can be associated with long-term adverse effects including cerebellar ataxia. Whilst phenytoin is toxic to Purkinje cells in vitro; the clinical and radiological phenotype and mechanism of cerebellar degeneration in vivo remain unclear. light x tour
Dilantin Effects Linked Brain Atrophy - Parker & Waichman
WebApr 15, 2024 · Serum phenytoin level was 42 µg/mL and serum valproate level was 64 µg/mL. MRI of the brain and spine showed calcified granuloma (right frontal lobe) and … WebFeb 17, 2024 · It is a sequela of chronic alcohol use or malnutrition. Terminology Alcoholic cerebellar degeneration has also been described in the literature as a lcohol-related cerebellar degeneration, alcohol-induced cerebellar degeneration and nutritional cerebellar degeneration 1,2. Epidemiology The prevalence is estimated at 12 – 27% from autopsies 2. WebMild overdosage of phenytoin produces reversible cerebellar symptoms (nystagmus, double vision, dysarthria and ataxia). Several case reports suggest that relatively mild and relatively short intoxication can lead to cerebellar degeneration. lightxuanshou