WebThiazide. Thiazide diuretic agents reduce urine calcium excretion, and have been used for that purpose for decades as a stone prevention. ... No one has found, thus far, any other way that thiazide can affect kidney stone production. Alkali salts. Bicarbonate, citrate salts, and in principle other citric acid cycle metabolites create an alkali ... Web13 Jan 2006 · Kidney stone formation due to an excess of calcium in the urine is a common problem. It is treated with thiazide diuretics. These drugs often cause excessively low blood potassium levels that in turn require large doses of potassium supplements. These supplements are often large, unpleasant and easy to forget.
Diuretics and calcium balance - UpToDate
Web11 Apr 2024 · The physiologic basis of thiazide use in kidney stone prevention is the reduction of urinary calcium excretion. This trial confirmed that patients on HCTZ had … Web1 Dec 2014 · Nephrolithiasis is a common condition worldwide with a prevalence of 5% to 10%. 1 Recent evidence has shown that kidney stones are becoming more common. 2 … lofty viewpoint definition
Prevention of calcium stones with thiazides - PubMed
Web11 Apr 2024 · The physiologic basis of thiazide use in kidney stone prevention is the reduction of urinary calcium excretion. This trial confirmed that patients on HCTZ had decreased urinary calcium excretion. However, urine relative supersaturation ratios for calcium oxalate and calcium phosphate were not lower among patients on HCTZ vs … Webthiazide diuretic. The image below can be used to understand the mechanism by which thiazide diuretics act to decrease calcium in the urine. Thiazide diuretics block Na+/Cl- symporters on the apical membrane of renal tubular cells in the DCT. This acts to decrease intracellular Na+ levels and thus increases the “driving force” for Na+ Web15 Jul 2024 · Background: Thiazide diuretics are commonly prescribed to prevent kidney stones. However, it is unclear whether higher doses confer greater benefit. Objective: To … lofty\u0027s lounge evansdale ia